The 49ers-Cardinals line and total didn't move prior to the Chargers-49ers kickoff. And much like the Chiefs game, we know what side we’ll need, given the point spread and the spot in the schedule.' 'We still don’t think much of the Cardinals. 'We opened 49ers -7.5 and closed the game when when Sunday Night Football kicked off,' Murray said.

In Week 10, the Cardinals were catching 3.5 points on the road and took down the defending Super Bowl champion Los Angeles Rams 27-17. That said, San Fran failed to cash as an 8.5-point home chalk.Īrizona (4-6 SU, 5-5 ATS) is trying to hang around in what's been a mediocre NFC West thus far. But the Niners took a 19-16 lead midway through the fourth quarter en route to a 22-16 victory. ET SUNDAY: San Francisco (5-4 SU, 4-5 ATS) trailed the Chargers most of the way in the Week 10 Sunday nighter. The total is painted to the 43.5 opener, with 55% of tickets on the Over/70% of cash on the Under. Spread ticket count is dead even, but spread money is nearly 6/1 on San Francisco. ET FRIDAY: The 49ers opened as 7.5-point favorites at Caesars Sports, moved to -8 Monday and haven't budged since then. The Over is seeing 58% of money, but 71% of handle is on the Under, a big increases from two hours ago, when 52% of cash was on the Under. The total opened at 43.5, fell to 43 Sunday and remains 43 this evening. We also have decent liability on Christian McCaffrey to score a TD, so it would be good for us if he stays out of the end zone.' 'The best-case scenario is probably just a 49ers cover. 'A bunch of action on the Niners moneyline, but more than 80% of spread handle on the Cards,' PointsBet sports analyst Mike Korn said. On the flip side, moneyline tickets and cash are 5/1 Niners. That noted, point-spread ticket count is 3/2 and spread money 5/1 on the Cardinals. However, on today's Murray news, the line leapt to 49ers -10, before nudging down to -9.5. San Francisco opened -8 a week ago, briefly touched -8.5 and -9 Tuesday, then stabilized at -8. With two-plus hours until kickoff, the 49ers are laying 9.5 points on PointsBet USA's NFL Week 11 odds board. Second, Kyler Murray (hamstring) is likely out tonight, and oddsmakers responded accordingly. ET MONDAY: First off, a reminder that tonight's game is a neutral-site contest, in Mexico City. Deebo Samuel and the 49ers outlasted the Chargers in Week 10.

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